Hoodia thin is a plant based product for the procedure of obesity which is now in clinical development. The product was licensed to Pfizer Inc in 1998 in a global licensing agreement. The cactus from which P57 was started from the hoodia gordoni plus Cactus plant species.

hoodia thin is a fully described extract started from a single plant which is subject to patent applications covering raw materials, active ingredients and mode of action. Hoodia complex resembles to have novel pharmacological properties and may in fact be the first ever true appetite suppressant to be discovered. Unlike many of the conventional treatments currently available it has no effects on behaviour. The mechanism of action is novel and distinct from those of presently available compounds. Efficacy has been established with a thoughtful weight loss and a excellent emergent safety profile.

hoodia seeds considerable progress has been achieved with this project. Phase I of hoodia thin clinical development moves alongside an extensive research program. In parallel to these activities, additional plantations for the plant material have been established world-wide in collaboration with the CSIR and Pfizer and a clinical supplies unit, dedicated to the manufacturer of the material, has been opened in South Africa.

Anecdotal reports of the use of hoodia thin in humans reveal that it significantly reduces appetite, food intake and body weight. Considerable work has been undertaken to fractionate this plant material and a number of compounds have been isolated from the mixture, some of which have biological activity. The mechanism of action of P57 and its active constituents is currently under investigation. Supplementary pharmacological properties have recently been established.

hoodia thin is an appetite suppressant with novel pharmacological properties that has no effects on behavior. It is educed from the hoodia gordonii plus, a South African plant which has been eaten by Bushmen for thousands of years to stave off thirst and hunger during long hunting trips. Phytopharm has six patents in progress covering the use of the plant, its active molecules, derivatives and mode of action. Once its patents are published the company will disclose the mode of action. Last year Dr. Richard Dixey, CEO of Phytopharm, told the Wall Street Transcript, “We will not disclose the mode of action at this time because hoodia thin is the subject of a very active patenting program. There is no point in early disclosure of such information until the patent is eventually publicized and the information enters the public domain. All one would be doing would be to give ones power competitors useful information and advise people to best hoodia“.

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