Hoodia xpf is a plant based product for the cure of obesity which is now in clinical development. The product was licensed to Pfizer Inc in 1998 in a global licensing agreement. The cactus from which P57 was created from the hoodia liquid extract Cactus plant species.

hoodia xpf is a fully specified extract created from a single plant which is subject to patent applications embracing raw materials, active chemicals and mode of action. Hoodia complex correspond to have novel pharmacological properties and may in fact be the first ever true appetite suppressant to be found. Unlike many of the conventional treatments presently available it has no effects on behaviour. The mechanism of action is novel and distinct from those of currently available compounds. Efficacy has been established with a thoughtful weight loss and a best value emergent safety profile.

hoodia seeds considerable progress has been achieved with this project. Phase I of hoodia xpf clinical development goes on and on alongside an extensive research program. In parallel to these activities, further plantations for the plant material have been established world-wide in collaboration with the CSIR and Pfizer and a clinical supplies unit, dedicated to the manufacturer of the material, has been opened in South Africa.

Anecdotal reports of the use of hoodia xpf in humans reveal that it significantly reduces appetite, food intake and body weight. Considerable work has been undertaken to fractionate this plant material and a number of compounds have been isolated from the mixture, some of which have biological activity. The mechanism of action of P57 and its active constituents is currently under investigation. Additional pharmacological properties have lately been established.

hoodia xpf is an appetite suppressant with novel pharmacological properties that has no effects on behavior. It is educed from the hoodia gordonii diet, a South African plant which has been eaten by Bushmen for thousands of years to hold off thirst and hunger during long hunting trips. Phytopharm has six patents in progress covering the use of the plant, its active molecules, derivatives and mode of action. Once its patents are published the company will disclose the mode of action. Last year Dr. Richard Dixey, CEO of Phytopharm, told the Wall Street Transcript, “We will not disclose the mode of action at this time because hoodia xpf is the subject of a very active patenting program. There is no point in early disclosure of such information until the patent is eventually published and the information enters the public domain. All one would be doing would be to give ones possible competitors useful information and suggest that people to buy hoodia online“.